Morpho-functional analysis of the Knee


In total knee replacement, the clinical outcome is significantly influenced by the implant design. Different concepts of gender-, race- or patient-specific designs have been developed. This is based on reported anatomical differences in the knee shape (morphology), as reported in literature. However, little is known whether these differences originate from phenotypic differences between men and women or different ethnicities, or e.g. overall body size, and thus can be eliminated by a simple scaling. Therefore, we develop parametric models to quantify the knee morphology. This includes fully automatic methods for landmark recognition and feature extraction. Subsequently, we use statistical, correlation, and cluster analysis to investigate the knee morphology for patient specific implant design.

Related topics

Publications

  • M. Asseln, C. Hänisch, F. Schick & K. Radermacher: Gender differences in knee morphology and the prospects for implant design in total knee replacement. The Knee, 2018, 25(4), pp. 545-558
  • M. Asseln, C. Hänisch & K. Radermacher: Normalization of the knee morphology using correlation analysis and its consequences for implant design. In: F. O'Brien & D. Kelly (ed.): 8th World Congress of Biomechanics, 2018, pp. O1834
  • M. Asseln, C. Hänisch, F. Schick & K. Radermacher: Analysis of Gender-Specific Aspects of the Morphology of the Distal Femur. In: K. Radermacher & F. Rodriguez Y Baena (ed.): CAOS2017. EPiC Series in Health Sciences, 1, 2017, pp. 238-243
  • M. Asseln, M. Fischer, C. Hänisch & K. Radermacher: Automatic Parameterization of the Proximal Tibia Based on 3D Surface Data for Morphological Analysis and Implant Optimization. 16th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 2016, pp. 325-328
  • M. Fischer, M. Asseln, G. Al Hares & K. Radermacher: Relationship between the functional finite helical axes and morphology-based axes of the knee. 16th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 2016, pp. 124-128
  • M. Asseln, C. Hänisch, G. Al Hares, J. Eschweiler & K. Radermacher: Automatic Parameterization Of The Distal Femur Based On 3d Surface Data: A Novel Approach For Systematic Morphological Analysis And Optimization. 15th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 2015, pp. 68
  • M. Asseln, C. Hänisch, G. Al Hares, V. Quack & K. Radermacher: A Mesh Morphing Based Method To Estimate Cruciate Ligament Attachments Based On CT-Data. 15th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 2015, pp. 60
  • M. Asseln, M. Fischer, G. Al Hares, V. Quack & K. Radermacher: Relationship Between The Distal Femoral Morphology And Cruciate Ligament Attachments. 15th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, 2015, pp. 62

Contact

Sonja Grothues, M.Sc.
Tel.: +49 (0)241-80 23863